Hypothesis / aims of study
Post-prostatectomy urinary incontinence (PPI) significantly impacts the quality of life (QoL) of patients undergoing robot-assisted radical prostatectomy (RARP). While pelvic floor muscle training (PFMT) is the first-line treatment, options for mild-to-moderate incontinence refractory to rehabilitation are limited, as invasive procedures like urethral slings are often not indicated. The aim of this study was to evaluate the safety and efficacy of a specific radiofrequency (RF) protocol in patients with residual PPI.
Study design, materials and methods
We enrolled 20 patients who underwent RARP for prostate adenocarcinoma at least one year prior, presenting with persistent mild-to-moderate incontinence (assessed via pad test) despite having completed at least 10 sessions of PFMT (Kegel, biofeedback, and probe stimulation) without benefit. The experimental protocol consisted of 15 RF sessions divided into two phases (external and endocavitary).
• Sessions 1-10: 1) External: static automatic mode (500 kHz, 10 min); 2) Endocavitary: dynamic neutral mode (athermal 1, 450 kHz, 10 min).
• Sessions 11-15: 1) External: static automatic mode (500 kHz, 10 min); 2) Endocavitary: dynamic neutral mode (continuous, 500 kHz, 10 min).
Treatment parameters monitored included impedance (Ohm), instantaneous output voltage (Vrms)—titrated based on patient tolerance—and total energy transferred (Jtot). Clinical outcomes were assessed via PC-test, pad test, tissue quality evaluation, PSA levels at 6 months, and QoL questionnaires.
Interpretation of results
Regarding continence recovery:
• 4 patients (20%) achieved complete resolution of incontinence.
• 14 patients (70%) reported improved QoL and reduced pad use.
• 2 patients, who entered the study with moderate-to-severe incontinence (off-label indication for comparison), did not benefit and were subsequently referred for surgical sling/sphincter implantation.