Onabotulinumtoxin A Intradetrusor Injection Procedure: an Observational Study of the Learning Curve of Nurse Team

Gubbiotti M1, Gilli C2, Bigazzi B1, Giommoni V1, Rosadi S1

Research Type

Clinical

Abstract Category

Overactive Bladder

Abstract 144
Urology 5 - Lower Urinary Tract Symptoms Therapy
Scientific Podium Short Oral Session 12
Friday 19th September 2025
10:22 - 10:30
Parallel Hall 3
Detrusor Overactivity Overactive Bladder Urgency Urinary Incontinence
1. S. Maria la Gruccia Hospital, dept. of Urology, Montevarchi (Ar), Italy, 2. University of Pisa, dept. of Urology, Pisa (Italy)
Presenter
Links

Abstract

Hypothesis / aims of study
Nurses are involved in different preoperative, perioperative and postoperative phases of treatment with intradetrusor injections of OnabotulinumtoxinA (Onabot/A). Little is known about the nursing expertise needed to perform the procedure safely. Aim of the study was to assess the learning curve of a nurse team for the Onabot/A procedure in out- patient setting.
Study design, materials and methods
After approval by our Institutional Review Board, we performed a pilot, prospective study. Nursing team of our center was recruited. We recorded nurse’s demographic, the number of procedures performed, the nurse team's preoperative, perioperative, and postoperative surgical time at baseline and at 6- months of the procedures performed. Nurses filled out the Nurse Competence Scale questionnaire (NCS-q) for the self- evaluation of clinical competence and underwent also to the VAS scale to evaluate the difficulty of learning the procedure (0: worst, 10: best). Additionally, we compared the surgical times of the Nurse Team under study with one Onabot/A injections expert nurse.
Results
Seven nurses were enrolled (mean age [SD]: 49.58.4). The mean(SD) procedures performed for each nurse was: 8.44.7. One experienced surgeon on Onabot/A injections completed all the 58 Onabot/A injections in out- patient clinical setting. Data on the time required for pre- and peri-operative preparation are reported in Table 1. The timelines show that work pattern stabilized after 7 Onabot/A injections but with a continued decrease in procedure time. VAS score: 3.22.1. The NCS-q domain category “Managing Situation” (8 items) showed a mean ( SD) of 8.10.3. The comparison of the time of the patient’s preparation between the expert nurse and the 6- month experience of the nurse team was: 111.9 vs 122.2 (p< 0.5).
Interpretation of results
To date, this is the first study assessing duration and efficacy of the nurses learning curve for Onabot/A injections in out-patient clinic. The threshold of procedures required to complete the learning curve was low and nurses achieved a high level of expertise within 7 procedures. After achieving this proficiency, a continuous decrease in times in all phases of treatment related to nurses was demonstrated. The strength of this study was to demonstrate for the first time, from a nursing perspective, how the learning curve for Onabot/A injections is simple and short for nurses.
Concluding message
The nurse's expertise in the Onabot/A procedure is important for a better performance in the treatment and proper support to the patient. For this reason, the training of the nurses who assist the procedure is an area to be followed with care.
Figure 1 Table 1. The nurse team's pre-operative, peri-operative and post- operative surgical time at baseline and at 6- months of the procedures performed.
Disclosures
Funding None Clinical Trial No Subjects Human Ethics Committee Local Ethics Committee Helsinki Yes Informed Consent Yes
03/07/2025 09:09:06