ICS 2018 Scientific Podium Short Oral Session S5

Speakers
	Scientific Podium Short Oral Session S5
	Wednesday 29th August 2018
	10:30 - 12:00
	Hall B Capacity: 400
	Lunch provided
K Karl-Erik Andersson ICS Chair L Larissa Virginia Rodriguez ICS Chair

10:30

#43 Sildenafil, a Phosphodiesterase Type 5 Inhibitor, augments bladder afferent activity in mouse.

Presenter: Hiroki Ito

Ito H¹, Chakrabarty B¹, Fry C H¹, Kanai A J², Drake M¹, Pickering A¹
1. School of Physiology, Pharmacology and Neuroscience, Faculty of Biomedical Sciences, University of Bristol, Bristol, BS8 1TD., 2. Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pennsylvania, USA.
Basic Science, Pharmacology, Physiology, Animal Study

10:37

#44 Central angiotensin II induces frequent urination through inhibition of GABAergic nervous system and stimulation of angiotensin II type 1 receptor downstream signaling in rats

Presenter: Takahiro Shimizu

Shimizu S¹, Shimizu T¹, Nakamura K¹, Higashi Y¹, Aratake T¹, Zou S¹, Hamada T¹, Nagao Y¹, Ueba Y¹, Yamamoto M¹, Honda M², Saito M¹
1. Department of Pharmacology, Kochi Medical School, Kochi University, Nankoku, Japan, 2. Division of Urology, School of Medicine, Tottori University, Yonago, Japan
Animal Study, Detrusor Overactivity, Basic Science, Pharmacology

10:45

#45 Effect of Lysophosphatidic Acid and ASP6432, a Novel Type 1 Lysophosphatidic Acid Receptor Antagonist, on Bladder Storage Function in Rats

Presenter: Kazuyuki Sakamoto

Sakamoto K¹, Noguchi Y¹, Ueshima K¹, Imazumi K¹, Ohtake A¹, Takeda M¹, Masuda N¹
1. Astellas Pharma Inc.
Basic Science, Detrusor Overactivity, Benign Prostatic Hyperplasia (BPH), Overactive Bladder, Pharmacology

10:52

#46 Inhibition of phosphodiesterase type 9 (PDE9) improves storage and voiding dysfunction in mice with spinal cord injury

Presenter: Nobutaka Shimizu

Shimizu N¹, Hashimoto M², Suzuki T³, Takaoka E³, Kwon J³, Shimizu T³, Wada N³, Hirayama A⁴, Uemura H², Kanai A J⁵, De Groat W C⁶, Yoshimura N³
1. Dept of Urology- University of Pittsburgh, Kindai University, Faculty of Medicine, 2. Dept of Urology-Kindai University, Faculty of Medicine, 3. Dept of Urology- University of Pittsburgh, 4. Dept of Urology- Kindai University Nara Hospital, Faculty of Medicine, 5. Dept of Medicine, University of Pittsburgh, 6. Dept of Pharmacology and Chemical Biology- University of Pittsburgh
Spinal Cord Injury, Voiding Dysfunction , Physiology, Detrusor Overactivity, Pharmacology

11:00

#47 Development of an in vitro urothelial cell culture model to study the effect of pannexin-1 channel on cytokine induced damage of urothelial integrity

Presenter: Kate H Moore

Sana-Ur-Rehman H¹, Moore K H², Mansfield K J³, Liu L¹
1. School of Medical Sciences, UNSW Sydney, Australia, 2. St George Hospital, Sydney, Australia, 3. School of Medicine, University of Wollongong, Australia
Basic Science, Cell Culture, Painful Bladder Syndrome/Interstitial Cystitis (IC), Pharmacology

11:07

#48 Involvement of piezo-1 ion channel in the regulation of acetylcholine release in the mouse urinary bladder

Presenter: Sajid Bashir

Bashir S¹, Sana-Ur-Rehman H¹, Noreen M², Ahsan H¹
1. College of Pharmacy, University of Sargodha, 2. Tehsil Headquater Hospital Hazro
Cell Culture, Pharmacology, Molecular Biology, Overactive Bladder

11:15

#49 Brain corticotropin-releasing factor receptor type 1 is involved in centrally administered bombesin-induced frequent urination in rats

Presenter: Takahiro Shimizu

Shimizu T¹, Zou S², Shimizu S², Wada N³, Takai S³, Shimizu N³, Yamamoto M², Higashi Y², Yoshimura N³, Saito M²
1. Department of Pharmacology, Kochi Medical School, Kochi University, Nankoku, Japan and Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, USA, 2. Department of Pharmacology, Kochi Medical School, Kochi University, Nankoku, Japan, 3. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, USA
Animal Study, Basic Science, Pharmacology

11:22

#50 Hydrogen sulfide has a role as an endogenous relaxation factor in the bladder and prostate of male rats

Presenter: Takahiro Shimizu

Shimizu T¹, Zou S¹, Shimizu S¹, Higashi Y¹, Nakamura K¹, Ono H¹, Aratake T¹, Yamamoto M¹, Honda M², Saito M¹
1. Department of Pharmacology, Kochi Medical School, Kochi University, Nankoku, Japan, 2. Division of Urology, Tottori University School of Medicine, Yonago, Japan
Animal Study, Basic Science, Male, Pharmacology

11:30

#51 Effects of RQ-00434739, a Transient Receptor Potential Melastatin 8 (TRPM8) channel antagonist, on deep body temperature and on bladder function in rats

Presenter: Naoki Aizawa

Aizawa N¹, Ohshiro H², Watanabe S², Kume H³, Igawa Y¹
1. Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, Tokyo, Japan, 2. RaQualia Pharma Inc., Nagoya, Japan,, 3. Department of Urology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan
Basic Science, Pharmacology, Physiotherapy, Animal Study

11:37

#52 Blockage of purinergic P2X7 receptor reduces mucosa damage and restores diminished contractility in an ex-vivo inflammation model of porcine bladder

Presenter: Kate H Moore

Taidi Z¹, Mansfield K J², Moore K H³, Liu L¹
1. School of Medical Sciences, UNSW Sydney, Australia, 2. School of Medical Sciences, University of Wollongong, Australia, 3. St George Hospital, UNSW Sydney, Australia
Painful Bladder Syndrome/Interstitial Cystitis (IC), Pharmacology, Basic Science

11:45

#53 The Role of Mitochondria in Irradiation-induced Urothelial Dysfunction—implications for Radiation Cystitis

Presenter: Irina Zabbarova

Ikeda Y¹, Kullmann F A¹, Zabbarova I¹, Wipf P¹, Birder L A¹, Kanai A J¹
1. University of Pittsburgh
Animal Study, Pathophysiology, Pharmacology

11:52

#54 Histamine H3 receptor inhibited the inflammatory response during C2C12 striated myogenesis induced by exogenous alpha tumor necrosis factor

Presenter: Jian Guo Wen

Chen Y¹, Xu P¹, He Y L¹, Feng J J¹, Yan S H¹, Li Y D¹, Li Y L¹, Wen J G¹
1. The First Affiliated Hospital of Zhengzhou University, Key Laboratory of Urology and the International Children's Urodynamic Center in Henan Province, China
Basic Science, Molecular Biology, Voiding Dysfunction , Cell Culture, Stem Cells / Tissue Engineering

Content Visitors (staff only)

Basic Science: Pharmacology

Session Schedule

Basic Science: Pharmacology

Session Schedule

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